1-[Bis(dimethylamino)methylene]-5-chloro-1-benzotriazolium 3-Oxide Tetrafluoroborate
N,N,N',N'-Tetramethyl-O-(6-chloro-1H-benzotriazol-1-yl)uronium tetrafluoroborate
CAS: 330641-16-2
Molecular Formula: C11H15BClF4N5O
1-[Bis(dimethylamino)methylene]-5-chloro-1-benzotriazolium 3-Oxide Tetrafluoroborate - Names and Identifiers
1-[Bis(dimethylamino)methylene]-5-chloro-1-benzotriazolium 3-Oxide Tetrafluoroborate - Physico-chemical Properties
| Molecular Formula | C11H15BClF4N5O |
| Molar Mass | 355.53 |
| Melting Point | 201-205°C |
| Solubility | DMF: 10%, clear |
| Appearance | White-like powder |
| Storage Condition | Inert atmosphere,2-8°C |
| MDL | MFCD04973270 |
1-[Bis(dimethylamino)methylene]-5-chloro-1-benzotriazolium 3-Oxide Tetrafluoroborate - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S60 - This material and its container must be disposed of as hazardous waste. S37 - Wear suitable gloves. |
| UN IDs | 1759 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10 |
| HS Code | 29339900 |
| Hazard Class | 8 |
| Packing Group | III |
1-[Bis(dimethylamino)methylene]-5-chloro-1-benzotriazolium 3-Oxide Tetrafluoroborate - Introduction
Polypeptide reagent TCTU(N,N,N',N'-tetramethyl-O-(6-chloro-1h-benzotriazol-1-yl) urea hydrochloride tetrafluoroborate) it is a commonly used activation reagent, which is commonly used in peptide synthesis and protein chemical modification in solid phase synthesis.
Nature:
TCTU exists in the form of colorless crystals or white powder, and is soluble in organic solvents such as acetonitrile, dimethyl sulfite and dimethylformamide.
Use:
TCTU can be used to synthesize polypeptide chains or to introduce various functional groups. It is widely used in solid phase synthesis in the introduction of dihydropyrrolyl (Dp), C- terminal acylation modification and isotope labeling reactions.
Method:
The preparation of TCTU usually uses a series of chemical reactions. The most common method is the reaction of N,N-dimethylurea together with 6-chloro-1H-benzotriazole and then with tetrafluoroboric acid to give TCTU.
Safety Information:
TCTU needs to pay attention to physical contact and inhalation during use. It is irritating to the skin, eyes and respiratory tract and can cause allergic reactions. Wear appropriate protective equipment such as gloves, goggles and protective masks when in use. At the same time, it should be operated in a well-ventilated place to avoid inhalation of toxic gases. In case of contact or inhalation, immediately flush the affected area with clean water and seek medical assistance.
Nature:
TCTU exists in the form of colorless crystals or white powder, and is soluble in organic solvents such as acetonitrile, dimethyl sulfite and dimethylformamide.
Use:
TCTU can be used to synthesize polypeptide chains or to introduce various functional groups. It is widely used in solid phase synthesis in the introduction of dihydropyrrolyl (Dp), C- terminal acylation modification and isotope labeling reactions.
Method:
The preparation of TCTU usually uses a series of chemical reactions. The most common method is the reaction of N,N-dimethylurea together with 6-chloro-1H-benzotriazole and then with tetrafluoroboric acid to give TCTU.
Safety Information:
TCTU needs to pay attention to physical contact and inhalation during use. It is irritating to the skin, eyes and respiratory tract and can cause allergic reactions. Wear appropriate protective equipment such as gloves, goggles and protective masks when in use. At the same time, it should be operated in a well-ventilated place to avoid inhalation of toxic gases. In case of contact or inhalation, immediately flush the affected area with clean water and seek medical assistance.
Last Update：2024-04-09 21:11:58
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Product Name: O-(6-Chloro-1-hydrocibenzotriazol-1-yl)- -1,1,3,3-tetramethyluronium tetrafluoroborate Visit Supplier Webpage Request for quotationCAS: 330641-16-2
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Spot supply
Product Name: O-(6-Chloro-1-hydrocibenzotriazol-1-yl)- -1,1,3,3-tetramethyluronium tetrafluoroborate Visit Supplier Webpage Request for quotationCAS: 330641-16-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
1-[Bis(dimethylamino)methylene]-5-chloro-1-benzotriazolium 3-Oxide Tetrafluoroborate
环十二醇
半干 (METALS BASIS)
88744-36-9
环十二醇
半干 (METALS BASIS)
88744-36-9